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WISP3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21363N-1 50ul / $395
APR21363N-2 100ul / $495
APR21363N-3 200ul / $595

WISP3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21363N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Growth factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality WISP3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 39kDa/41kDa Observed MW: 41kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human WISP3 (NP_937882.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

WISP3; CCN6; LIBC; PPAC; PPD; WISP-3; WNT1-inducible-signaling pathway protein 3

Images

Western blot analysis of extracts of various cell lines, using WISP3 antibody.

Specification

Quantity

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