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COX15 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21219N-1 50ul / $395
APR21219N-2 100ul / $495
APR21219N-3 200ul / $595

COX15 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21219N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Mitochondrial metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COX15 Polyclonal Antibody.

Molecular Weight

Calculated MW: 43kDa/46kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human COX15 (NP_510870.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region.

Synonyms

COX15; CEMCOX2; COX15, cytochrome c oxidase assembly homolog

Images

Western blot analysis of extracts of various cell lines, using COX15 antibody.

Immunohistochemistry of paraffin-embedded rat spleen using COX15 antibody.

Immunohistochemistry of paraffin-embedded rat heart using COX15 antibody.

Specification

Quantity

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