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IDH3A Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR21207N-1 50ul / $395
APR21207N-2 100ul / $495
APR21207N-3 200ul / $595

IDH3A Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR21207N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Mitochondrial metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IDH3A Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/40kDa Observed MW: 40kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human IDH3A (NP_005521.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Synonyms

IDH3A; isocitrate dehydrogenase 3 (NAD(+)) alpha

Images

Western blot analysis of extracts of various cell lines, using IDH3A antibody.

Immunohistochemistry of paraffin-embedded rat kidney using IDH3A antibody.

Immunohistochemistry of paraffin-embedded human thyroid cancer using IDH3A antibody.

Specification

Quantity

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