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CDH3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20780N-1 50ul / $395
APR20780N-2 100ul / $495
APR20780N-3 200ul / $595

CDH3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20780N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDH3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 86kDa/91kDa Observed MW: 115kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CDH3 (NP_001784.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).

Synonyms

CDH3; CDHP; HJMD; PCAD; cadherin-3

Images

Western blot analysis of extracts of various cell lines, using CDH3 antibody.

Immunohistochemistry of paraffin-embedded human skin using CDH3 antibody.

Specification

Quantity

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