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RNF8 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20637N-1 50ul / $395
APR20637N-2 100ul / $495
APR20637N-3 200ul / $595

RNF8 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20637N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Ubiquitin

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNF8 Polyclonal Antibody.

Molecular Weight

Calculated MW: 10kDa/50kDa/55kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RNF8 (NP_003949.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.

Synonyms

RNF8; hRNF8; ring finger protein 8

Images

Immunofluorescence analysis of MCF-7 cells using RNF8 antibody.

Specification

Quantity

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