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PTPN22 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20617N-1 50ul / $395
APR20617N-2 100ul / $495
APR20617N-3 200ul / $595

PTPN22 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20617N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Jak-Stat-IL-6 Receptor Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPN22 Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/75kDa/78kDa/85kDa/88kDa/91kDa Observed MW: 107kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PTPN22 (NP_036543.4).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Synonyms

PTPN22; LYP; LYP1; LYP2; PEP; PTPN22.5; PTPN22.6; PTPN8; tyrosine-protein phosphatase non-receptor type 22

Images

Western blot analysis of extracts of various cell lines, using PTPN22 antibody.

Immunofluorescence analysis of C6 cells using PTPN22 antibody.

Immunofluorescence analysis of L-929 cells using PTPN22 antibody.

Specification

Quantity

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