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PLAUR Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20532N-1 50ul / $395
APR20532N-2 100ul / $495
APR20532N-3 200ul / $595

PLAUR Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20532N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Blood

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLAUR Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/32kDa/36kDa Observed MW: 36-72kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PLAUR (NP_002650.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Synonyms

PLAUR; CD87; U-PAR; UPAR; URKR; plasminogen activator, urokinase receptor

Images

Western blot analysis of extracts of various cell lines, using PLAUR antibody.

Specification

Quantity

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