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CYP17A1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20530N-1 50ul / $395
APR20530N-2 100ul / $495
APR20530N-3 200ul / $595

CYP17A1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20530N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Growth factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP17A1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 57kDa Observed MW: 57kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CYP17A1 (NP_000093.1).

Cross Reactivity

Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Synonyms

CYP17A1; CPT7; CYP17; P450C17; S17AH; steroid 17-alpha-hydroxylase/17,20 lyase

Images

Western blot analysis of extracts of rat testis, using CYP17A1 antibody.

Immunohistochemistry of paraffin-embedded rat brain using CYP17A1 Antibody.

Specification

Quantity

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