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RBBP4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20496N-1 50ul / $395
APR20496N-2 100ul / $495
APR20496N-3 200ul / $595

RBBP4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20496N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RBBP4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 43kDa/46kDa/47kDa Observed MW: 48kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RBBP4 (NP_005601.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF,ChIP

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200 ChIP 1:20 - 1:50

Product Description

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms

RBBP4; NURF55; RBAP48; lin-53; histone-binding protein RBBP4

Images

Western blot analysis of extracts of various cell lines, using RBBP4 antibody.

Specification

Quantity

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