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SNAP23 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20473N-1 50ul / $395
APR20473N-2 100ul / $495
APR20473N-3 200ul / $595

SNAP23 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20473N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Cell Type Marker

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SNAP23 Polyclonal Antibody.

Molecular Weight

Calculated MW: 17kDa/23kDa Observed MW: 23kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SNAP23 (NP_003816.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:100 - 1:200

Product Description

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Synonyms

SNAP23; HsT17016; SNAP-23; SNAP23A; SNAP23B; synaptosome associated protein 23

Images

Western blot analysis of extracts of various cell lines, using SNAP23 antibody.

Specification

Quantity

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