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RIN2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20365N-1 50ul / $395
APR20365N-2 100ul / $495
APR20365N-3 200ul / $595

RIN2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20365N

Product Type

Polyclonal Antibodies

Field of Research

Signal Transduction>G protein signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RIN2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 100kDa/105kDa Observed MW: 120kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human RIN2 (NP_061866.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

Synonyms

RIN2; MACS; RASSF4; ras and Rab interactor 2

Images

Western blot analysis of extracts of various cell lines, using RIN2 antibody.

Specification

Quantity

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