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CLCN4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20358N-1 50ul / $395
APR20358N-2 100ul / $495
APR20358N-3 200ul / $595

CLCN4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20358N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLCN4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 74kDa/84kDa Observed MW: 85kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CLCN4 (NP_001821.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.

Synonyms

CLCN4; CLC4; ClC-4; ClC-4A; MRX15; MRX49; chloride voltage-gated channel 4

Images

Western blot analysis of extracts of various cell lines, using CLCN4 antibody.

Specification

Quantity

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