> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CAMLG Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR20290N |
Product Type |
Polyclonal Antibodies | Field of Research |
Neuroscience>Calcium Signaling |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CAMLG Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
32kDa
Observed MW:
38kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human CAMLG (NP_001736.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200
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Product Description |
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
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Synonyms |
CAMLG; CAML; GET2; calcium modulating ligand
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Images |
Western blot analysis of extracts of various cell lines, using CAMLG antibody.
Immunohistochemistry of paraffin-embedded human breast cancer using CAMLG antibody.
Immunohistochemistry of paraffin-embedded human stomach using CAMLG antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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