> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > IRF8 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR20249N |
Product Type |
Polyclonal Antibodies | Field of Research |
Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IRF8 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
48kDa
Observed MW:
48kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human IRF8 (NP_002154.1).
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IF
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Dilution |
WB 1:500 - 1:2000
IF 1:50 - 1:200
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Product Description |
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
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Synonyms |
IRF8; H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8; interferon regulatory factor 8
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Images |
Western blot analysis of extracts of THP-1 cells, using IRF8 antibody.
Immunofluorescence analysis of A549 cells using IRF8 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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