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CD44 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20099N-1 50ul / $395
APR20099N-2 100ul / $495
APR20099N-3 200ul / $595

CD44 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20099N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>CDs

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD44 Polyclonal Antibody.

Molecular Weight

Calculated MW: 3kDa/15kDa/32-53kDa/73-81kDa Observed MW: 82kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CD44 (NP_001001389.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Synonyms

CD44; CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CD44 antigen

Images

Western blot analysis of extracts of various cell lines, using CD44 antibody.

Immunohistochemistry of paraffin-embedded human tonsil using CD44 antibody.

Immunohistochemistry of paraffin-embedded human colon carcinoma using CD44 antibody.

Specification

Quantity

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