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BCL2L2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20061N-1 50ul / $395
APR20061N-2 100ul / $495
APR20061N-3 200ul / $595

BCL2L2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20061N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BCL2L2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 20kDa/37kDa Observed MW: 27kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human BCL2L2 (NP_001186768.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Synonyms

BCL2L2; BCL-W; BCL2-L-2; BCLW; PPP1R51; BCL2 like 2

Images

Western blot analysis of extracts of mouse intestine, using BCL2L2 antibody.

Immunohistochemistry of paraffin-embedded rat liver using BCL2L2 antibody.

Immunohistochemistry of paraffin-embedded human mammary cancer using BCL2L2 antibody.

Specification

Quantity

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