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HAVCR2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR20033N-1 50ul / $395
APR20033N-2 100ul / $495
APR20033N-3 200ul / $595

HAVCR2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR20033N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HAVCR2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 16kDa/33kDa Observed MW: 35kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human HAVCR2 (NP_116171.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Synonyms

HAVCR2; CD366; HAVcr-2; KIM-3; TIM3; TIMD-3; TIMD3; Tim-3; hepatitis A virus cellular receptor 2

Images

Immunofluorescence analysis of Hela cells using HAVCR2 antibody.

Specification

Quantity

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