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DRD4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19961N-1 50ul / $395
APR19961N-2 100ul / $495
APR19961N-3 200ul / $595

DRD4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19961N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DRD4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 48kDa Observed MW: 52kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human DRD4 (NP_000788.2).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:200

Product Description

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Synonyms

DRD4; D4DR; dopamine receptor D4

Images

Western blot analysis of extracts of various cell lines, using DRD4 antibody.

Immunohistochemistry of paraffin-embedded rat retina using DRD4 antibody.

Specification

Quantity

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