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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Histone H2A.Z Polyclonal Antibody

Histone H2A.Z Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR19071N-1 50ul / $395
APR19071N-2 100ul / $495
APR19071N-3 200ul / $595

Histone H2A.Z Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR19071N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Histone H2A.Z Polyclonal Antibody.

Molecular Weight

Calculated MW: 13kDa Observed MW: 14kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human H2AFZ (NP_002097.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Product Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Synonyms

H2AFZ; H2A.Z-1; H2A.z; H2A/z; H2AZ; histone H2A.Z

Images

Western blot analysis of extracts of various cell lines, using Histone H2A.Z antibody.

Specification

Quantity

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