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MYBPC3 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18981N-1 50ul / $395
APR18981N-2 100ul / $495
APR18981N-3 200ul / $595

MYBPC3 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18981N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYBPC3 Polyclonal Antibody.

Molecular Weight

Calculated MW: 140kDa Observed MW: 170kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human MYBPC3 (NP_000247.2).

Cross Reactivity

Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Synonyms

MYBPC3; CMD1MM; CMH4; FHC; LVNC10; MYBP-C; myosin binding protein C, cardiac

Images

Western blot analysis of extracts of rat heart, using MYBPC3 antibody.

Specification

Quantity

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