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ABCD1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18821N-1 50ul / $395
APR18821N-2 100ul / $495
APR18821N-3 200ul / $595

ABCD1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18821N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Lipid Metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ABCD1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 82kDa Observed MW: 83kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ABCD1 (NP_000024.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Synonyms

ABCD1; ABC42; ALD; ALDP; AMN; ATP binding cassette subfamily D member 1

Images

Western blot analysis of extracts of various cell lines, using ABCD1 antibody.

Immunofluorescence analysis of NIH/3T3 cells using ABCD1 antibody.

Specification

Quantity

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