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NLRP11 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18812N-1 50ul / $395
APR18812N-2 100ul / $495
APR18812N-3 200ul / $595

NLRP11 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18812N

Product Type

Polyclonal Antibodies

Field of Research

Immunology & Inflammation>Cell Intrinsic Innate Immunity Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NLRP11 Polyclonal Antibody.

Molecular Weight

Calculated MW: 105kDa/111kDa/117kDa Observed MW: 110kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NLRP11 (NP_659444.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Product Description

This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms.

Synonyms

NLRP11; CLR19.6; NALP11; NOD17; PAN10; PYPAF6; PYPAF7; NLR family pyrin domain containing 11

Images

Western blot analysis of extracts of 293T cells, using NLRP11 antibody.

Specification

Quantity

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