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ABCA4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18171N-1 50ul / $395
APR18171N-2 100ul / $495
APR18171N-3 200ul / $595

ABCA4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18171N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ABCA4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 255kDa Observed MW: 256kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human ABCA4 (NP_000341.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IF

Dilution

WB 1:1000 - 1:2000 IF 1:50 - 1:200

Product Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Synonyms

ABCA4; ABC10; ABCR; ARMD2; CORD3; FFM; RMP; RP19; STGD; STGD1; ATP binding cassette subfamily A member 4

Images

Western blot analysis of extracts of various cell lines, using ABCA4 antibody.

Immunofluorescence analysis of HeLa cells using ABCA4 antibody.

Specification

Quantity

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