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DVL1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18149N-1 50ul / $395
APR18149N-2 100ul / $495
APR18149N-3 200ul / $595

DVL1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18149N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Hippo Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DVL1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 72kDa/75kDa Observed MW: 72kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human DVL1 (NP_004412.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Synonyms

DVL1; DRS2; DVL; DVL1L1; DVL1P1; dishevelled segment polarity protein 1

Images

Western blot analysis of extracts of Mouse kidney, using DVL1 antibody.

Immunohistochemistry of paraffin-embedded rat testis using DVL1 antibody.

Immunohistochemistry of paraffin-embedded mouse testis using DVL1 antibody.

Specification

Quantity

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