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COL11A2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18099N-1 50ul / $395
APR18099N-2 100ul / $495
APR18099N-3 200ul / $595

COL11A2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18099N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COL11A2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa/159-171kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human COL11A2 (NP_542411.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

Synonyms

COL11A2; DFNA13; DFNB53; FBCG2; HKE5; PARP; STL3; collagen alpha-2(XI) chain

Images

Western blot analysis of extracts of various cell lines, using COL11A2 antibody.

Specification

Quantity

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