> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TYMS Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR18064N |
Product Type |
Polyclonal Antibodies | Field of Research |
Endocrine & Metabolism>Nucleotide metabolism |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TYMS Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
26kDa/31kDa/35kDa
Observed MW:
36kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human TYMS (NP_001062.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IF
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Dilution |
WB 1:500 - 1:2000
IF 1:50 - 1:200
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Product Description |
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
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Synonyms |
TYMS; HST422; TMS; TS; thymidylate synthase
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Images |
Western blot analysis of extracts of various cell lines, using TYMS antibody.
Immunofluorescence analysis of C6 cells using TYMS antibody.
Immunofluorescence analysis of NIH/3T3 cells using TYMS antibody. |
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Specification |
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Quantity |
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Leading Biology Inc.
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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