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STC2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18022N-1 50ul / $395
APR18022N-2 100ul / $495
APR18022N-3 200ul / $595

STC2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18022N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Calcium Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STC2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 33kDa Observed MW: 25-33kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human STC2 (NP_003705.1).

Cross Reactivity

Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Synonyms

STC2; STC-2; STCRP; stanniocalcin-2

Images

Western blot analysis of extracts of various cell lines, using STC2 antibody.

Specification

Quantity

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