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HLA-F Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR18009N-1 50ul / $395
APR18009N-2 100ul / $495
APR18009N-3 200ul / $595

HLA-F Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR18009N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HLA-F Polyclonal Antibody.

Molecular Weight

Calculated MW: 28kDa/39kDa/50kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HLA-F (NP_001091949.1).

Cross Reactivity

Human,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

Synonyms

HLA-F; CDA12; HLA-5.4; HLA-CDA12; HLAF; major histocompatibility complex, class I, F

Images

Western blot analysis of extracts of A-549 cells, using HLA-F antibody.

Specification

Quantity

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