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KIF14 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17899N-1 50ul / $395
APR17899N-2 100ul / $495
APR17899N-3 200ul / $595

KIF14 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17899N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIF14 Polyclonal Antibody.

Molecular Weight

Calculated MW: 186kDa Observed MW: 190kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human KIF14 (NP_055690.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:1000 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.

Synonyms

KIF14; MKS12; kinesin family member 14

Images

Western blot analysis of extracts of various cell lines, using KIF14 antibody.

Immunohistochemistry of paraffin-embedded rat ovary using KIF14 antibody.

Immunohistochemistry of paraffin-embedded rat heart using KIF14 antibody.

Specification

Quantity

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