> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > KIF14 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR17899N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Cytoskeleton |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KIF14 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
186kDa
Observed MW:
190kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human KIF14 (NP_055690.1).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:1000 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
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Product Description |
This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.
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Synonyms |
KIF14; MKS12; kinesin family member 14
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Images |
Western blot analysis of extracts of various cell lines, using KIF14 antibody.
Immunohistochemistry of paraffin-embedded rat ovary using KIF14 antibody.
Immunohistochemistry of paraffin-embedded rat heart using KIF14 antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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