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SH3BP2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17866N-1 50ul / $395
APR17866N-2 100ul / $495
APR17866N-3 200ul / $595

SH3BP2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17866N

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SH3BP2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 10kDa/62kDa/65kDa/68kDa Observed MW: 75kDa/80kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SH3BP2 (NP_001116153.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

SH3BP2; 3BP-2; 3BP2; CRBM; CRPM; RES4-23; SH3 domain-binding protein 2

Images

Western blot analysis of extracts of various cell lines, using SH3BP2 antibody.

Specification

Quantity

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