> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] KRT8 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR17862N |
Product Type |
Polyclonal Antibodies | Field of Research |
Cell Biology & Developmental Biology>Cell Adhesion |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality [KO Validated] KRT8 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
53kDa/56kDa
Observed MW:
53kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human KRT8 (NP_002264.1).
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Cross Reactivity |
Human,Mouse
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IF
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
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Product Description |
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
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Synonyms |
KRT8; CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; keratin 8
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Images |
Western blot analysis of extracts of various cell lines, using KRT8 antibody.
Western blot analysis of extracts from normal (control) and KRT8 knockout (KO) HeLa cells, using KRT8 antibody.
Immunohistochemistry of paraffin-embedded human esophagus using KRT8 Antibody. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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