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GFM2 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17790N-1 50ul / $395
APR17790N-2 100ul / $495
APR17790N-3 200ul / $595

GFM2 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17790N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>Mitochondrial metabolism

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GFM2 Polyclonal Antibody.

Molecular Weight

Calculated MW: 57kDa/67kDa/81kDa/86kDa Observed MW: 86kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human GFM2 (NP_115756.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:1000 - 1:4000

Product Description

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Synonyms

GFM2; EF-G2mt; EFG2; MRRF2; MST027; MSTP027; RRF2; RRF2mt; hEFG2; mEF-G 2; mEF-G2; G elongation factor mitochondrial 2

Images

Western blot analysis of extracts of various cell lines, using GFM2 antibody.

Specification

Quantity

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