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NRXN1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17701N-1 50ul / $395
APR17701N-2 100ul / $495
APR17701N-3 200ul / $595

NRXN1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17701N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Adhesion

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NRXN1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 15kDa/46kDa/161kDa/164kDa/169kDa Observed MW: 162kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NRXN1 (NP_001129131.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission, and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. The RefSeq project has decided to create only a few representative transcript variants of the multitude that are possible. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2.

Synonyms

NRXN1; Hs.22998; PTHSL2; SCZD17; neurexin-1

Images

Western blot analysis of extracts of various cell lines, using NRXN1 antibody.

Specification

Quantity

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