> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > UGT1A6 Polyclonal AntibodyBrand |
Leading Biology | Catalog Number |
APR17668N |
Product Type |
Polyclonal Antibodies | Field of Research |
Endocrine & Metabolism>Drug metabolism |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UGT1A6 Polyclonal Antibody.
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Molecular Weight |
Calculated MW:
29kDa/50kDa/60kDa
Observed MW:
75kDa
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Species Reactivity |
Rabbit
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Immunogen |
Recombinant fusion protein of human UGT1A6 (NP_001063.2).
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Cross Reactivity |
Human,Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC
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Dilution |
WB 1:500 - 1:1000
IHC 1:50 - 1:100
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Product Description |
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
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Synonyms |
UGT1A6; GNT1; HLUGP; HLUGP1; UDPGT; UDPGT 1-6; UGT1; UGT1A6S; UGT1F; UDPGT1-6; UDP-glucuronosyltransferase 1-6
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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