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MARCKS Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17591N-1 50ul / $395
APR17591N-2 100ul / $495
APR17591N-3 200ul / $595

MARCKS Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17591N

Product Type

Polyclonal Antibodies

Field of Research

Neuroscience>Calcium Signaling

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MARCKS Polyclonal Antibody.

Molecular Weight

Calculated MW: 31kDa Observed MW: 80kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human MARCKS (NP_002347.5).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Synonyms

MARCKS; 80K-L; MACS; PKCSL; PRKCSL; myristoylated alanine-rich C-kinase substrate

Images

Western blot analysis of extracts of rat brain, using MARCKS antibody.

Specification

Quantity

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