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CEBPA Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17579N-1 50ul / $395
APR17579N-2 100ul / $495
APR17579N-3 200ul / $595

CEBPA Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17579N

Product Type

Polyclonal Antibodies

Field of Research

Cardiovascular>Lipids

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CEBPA Polyclonal Antibody.

Molecular Weight

Calculated MW: 25kDa/35kDa/37kDa/41kDa Observed MW: 41kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human CEBPA (NP_004355.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Synonyms

CEBPA; C/EBP-alpha; CEBP; CCAAT/enhancer-binding protein alpha

Images

Western blot analysis of extracts of mouse lung, using CEBPA antibody.

Immunohistochemistry of paraffin-embedded rat liver using CEBPA antibody.

Immunohistochemistry of paraffin-embedded rat brain using CEBPA antibody.

Specification

Quantity

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