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GRB10 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17495N-1 50ul / $395
APR17495N-2 100ul / $495
APR17495N-3 200ul / $595

GRB10 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17495N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Growth factors

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRB10 Polyclonal Antibody.

Molecular Weight

Calculated MW: 60kDa/62kDa/66kDa/67kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

A synthetic peptide of human GRB10 (NP_005302.3).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:1000

Product Description

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.

Synonyms

GRB10; GRB-IR; Grb-10; IRBP; MEG1; RSS; growth factor receptor-bound protein 10

Images

Western blot analysis of extracts of HeLa cells, using GRB10 antibody.

Specification

Quantity

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