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SSB Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17493N-1 50ul / $395
APR17493N-2 100ul / $495
APR17493N-3 200ul / $595

SSB Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17493N

Product Type

Polyclonal Antibodies

Field of Research

Epigenetics & Nuclear Signaling>RNA Binding

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SSB Polyclonal Antibody.

Molecular Weight

Calculated MW: 46kDa Observed MW: 47kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human SSB (NP_003133.1).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

Synonyms

SSB; LARP3; La; La/SSB; lupus La protein

Images

Western blot analysis of extracts of various cell lines, using SSB antibody.

Immunohistochemistry of paraffin-embedded human prostate cancer using SSB antibody.

Immunohistochemistry of paraffin-embedded human stomach using SSB antibody.

Specification

Quantity

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