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NEDD4 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17472N-1 50ul / $395
APR17472N-2 100ul / $495
APR17472N-3 200ul / $595

NEDD4 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17472N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NEDD4 Polyclonal Antibody.

Molecular Weight

Calculated MW: 104kDa/140kDa/147kDa/149kDa Observed MW: 120kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human NEDD4 (NP_940682.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.

Synonyms

NEDD4; NEDD4-1; RPF1; E3 ubiquitin-protein ligase NEDD4

Images

Western blot analysis of extracts of various cell lines, using NEDD4 antibody.

Immunohistochemistry of paraffin-embedded human prostate using NEDD4 antibody.

Immunohistochemistry of paraffin-embedded human gastric using NEDD4 antibody.

Specification

Quantity

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