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PRKCD Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17456N-1 50ul / $395
APR17456N-2 100ul / $495
APR17456N-3 200ul / $595

PRKCD Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17456N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRKCD Polyclonal Antibody.

Molecular Weight

Calculated MW: 77kDa/80kDa Observed MW: 78kDa/85kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human PRKCD (NP_997704.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Synonyms

PRKCD; ALPS3; CVID9; MAY1; PKCD; nPKC-delta; protein kinase C delta

Images

Western blot analysis of extracts of various cell lines, using PKCδ antibody.

Immunohistochemistry of paraffin-embedded rat lung using PKCδ antibody.

Immunohistochemistry of paraffin-embedded human tonsil using PKCδ antibody.

Specification

Quantity

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