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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] Fatty Acid Synthase Polyclonal Antibody

[KO Validated] Fatty Acid Synthase Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17453N-1 50ul / $395
APR17453N-2 100ul / $495
APR17453N-3 200ul / $595

[KO Validated] Fatty Acid Synthase Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17453N

Product Type

Polyclonal Antibodies

Field of Research

Endocrine & Metabolism>AMPK Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] Fatty Acid Synthase Polyclonal Antibody.

Molecular Weight

Calculated MW: 273kDa Observed MW: 275kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human Fatty Acid Synthase (NP_004095.4).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF,IP

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Product Description

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Synonyms

FASN; FAS; OA-519; SDR27X1; fatty acid synthase

Images

Western blot analysis of extracts of H460 cells, using Fatty Acid Synthase antibody.

Western blot analysis of extracts from normal (control) and Fatty Acid Synthase knockout (KO) 293T cells, using Fatty Acid Synthase antibody.

Immunohistochemistry of paraffin-embedded human colon using Fatty Acid Synthase antibody.

Specification

Quantity

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