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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > [KO Validated] HDAC1 Polyclonal Antibody

[KO Validated] HDAC1 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17360N-1 50ul / $395
APR17360N-2 100ul / $495
APR17360N-3 200ul / $595

[KO Validated] HDAC1 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17360N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] HDAC1 Polyclonal Antibody.

Molecular Weight

Calculated MW: 55kDa Observed MW: 62kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human HDAC1 (NP_004955.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF,IP

Dilution

WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:100

Product Description

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Synonyms

HDAC1; GON-10; HD1; RPD3; RPD3L1; histone deacetylase 1

Images

Western blot analysis of extracts of various cell lines, using HDAC1 antibody.

Western blot analysis of extracts from normal (control) and HDAC1 knockout (KO) 293T cells, using HDAC1 antibody.

Immunohistochemistry of paraffin-embedded human prostate cancer using HDAC1 antibody.

Specification

Quantity

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