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LRP5 Polyclonal Antibody

Catalog # Availability Size / Price Inquiry
APR17306N-1 50ul / $395
APR17306N-2 100ul / $495
APR17306N-3 200ul / $595

LRP5 Polyclonal Antibody

Brand

Leading Biology

Catalog Number

APR17306N

Product Type

Polyclonal Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LRP5 Polyclonal Antibody.

Molecular Weight

Calculated MW: 179kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

Recombinant fusion protein of human LRP5 (NP_002326.2).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Product Description

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.

Synonyms

LRP5; BMND1; EVR1; EVR4; HBM; LR3; LRP-5; LRP7; OPPG; OPS; OPTA1; VBCH2; LDL receptor related protein 5

Images

Western blot analysis of extracts of various cell lines, using LRP5 antibody.

Immunohistochemistry of paraffin-embedded human liver using LRP5 antibody.

Immunohistochemistry of paraffin-embedded human prostate using LRP5 antibody.

Specification

Quantity

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