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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > P2Y14 Receptor (extracellular) Antibody

P2Y14 Receptor (extracellular) Antibody

Catalog # Availability Size / Price Inquiry
APR17720G 50 μl / $695

P2Y14 Receptor (extracellular) Antibody

Brand

Leading Biology

Catalog Number

APR17720G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality P2Y14 Receptor (extracellular) antibody.

Molecular Weight

38971 Da

Host

Rabbit

Species Reactivity

Human, Rat

Target

Peptide CIELKSELGRKWHKASN, corresponding to amino acid?residues 172-188 of human P2Y14 (Accession# Q15391). 2nd extracellular loop.

GeneID

UniProt ID

Summary

P2Y14 belongs to the P2Y receptor family that is part of the G-protein coupled receptor superfamily. To date eight functional mammalian P2Y receptors have been identified: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13 and P2Y14.The P2Y receptor family mediates the effects of extracellular nucleotides such as ATP, ADP, UTP and in the case of P2Y14 UDP-glucose. UDP-glucose as the other nucleotides can be released to the extracellular milieu as the result of cell damage or by regulated non-lytic mechanisms.P2Y14 is expressed in several tissues including brain, lung and several cells of hematopoietic origin such as T lymphocytes and dendritic cells.The exact function of this receptor in the different tissues has not been clearly established but an involvement in chemotaxis, maturation of immature dendritic cells and neuroimmune regulation has been suggested.Abgent is pleased to offer a highly specific antibody directed against a conserved epitope in the second extracellular loop of the human P2Y14 receptor. Anti-P2Y14 (extracellular) antibody (#AG1064) can be used in Western blot analysis, and will recognize human and mouse samples.

Form

Affinity purified antibody, Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC

Dilution

WB~~1:200-1:2000 FC~~1:40

Synonyms

P2Y purinoceptor 14, P2Y14, G-protein coupled receptor 105, UDP-glucose receptor, P2RY14, GPR105, KIAA0001

Images

Western blot analysis of lysate from rat heart tissue lysate, using P2RY14 Antibody( APR17720G). APR17720G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Flow cytometric analysis of Jurkat cells using Park7 (DJ-1) Antibody(green, APR17720G) compared to an isotype control of rabbit IgG(blue). APR17720G was diluted at 1:40 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

Western blot analysis of rat heart membranes (lanes 1,4), rat brain (lanes 2,5) and rat lung lysates (lanes 3,6): 1-3. Anti-P2Y14 Receptor (extracellular) antibody, ( APR17720G), (1:200). 4-6. Anti-P2Y14 Receptor (extracellular) antibody, preincubated with the control peptide antigen.

Specification

Quantity

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