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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Somatostatin Receptor Type I (extracellular) Antibody

Somatostatin Receptor Type I (extracellular) Antibody

Catalog # Availability Size / Price Inquiry
APR13446G 50 μl / $695

Somatostatin Receptor Type I (extracellular) Antibody

Brand

Leading Biology

Catalog Number

APR13446G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Somatostatin Receptor Type I (extracellular) antibody.

Molecular Weight

42746 Da

Host

Rabbit

Species Reactivity

Rat

Target

Peptide CSRGPGSGAADGMEE, corresponding to amino acid?residues 26-40 of rat somatostatin receptor type 1 (Accession# P28646). Extracellular, N-terminus.

GeneID

UniProt ID

Summary

Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both stimulatory and inhibitory manner.1, 2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2 Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4Abgent is pleased to offer a highly specific antibody directed against the N-terminus domain of the rat SSTR1. Anti-Somatostatin Receptor Type 1 antibody (#AG1021), can be used in western blot analysis, and recognizes SSTR1 in rat samples.

Form

Affinity purified antibody, Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~1:200-1:2000

Synonyms

Somatostatin receptor type 1, SS-1-R, SS1-R, SS1R, SRIF-2, Sstr1

Images

Western blot analysis of lysates from rat brain and mouse brain tissue lysate(from left to right), using Sstr1 Antibody( APR13446G). APR13446G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Western blot analysis of rat brain lysate: 1. Anti-Somatostatin Receptor Type 1 (extracellular) antibody ( APR13446G), (1:200). 2. Anti-Somatostatin Receptor Type 1 (extracellular) antibody, preincubated with the control peptide antigen.

Specification

Quantity

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