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SOX4 Antibody

Catalog # Availability Size / Price Inquiry
APR13470G 0.1 mg / $695

SOX4 Antibody

Brand

Leading Biology

Catalog Number

APR13470G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SOX4 antibody.

Molecular Weight

Predicted: 52 kDa Observed: 520 kDa

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:16631117}

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

SOX4; SOX4 antibody is human, mouse and rat reactive.

Isotype

IgG

GeneID

UniProt ID

Function

Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.

Summary

SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1,2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4,5).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of SOX4 in human testis tissue lysate with SOX4 antibody at 1 μg/ml.

Immunohistochemistry of SOX4 in rat testis tissue with SOX4 antibody at 5 μg/mL.

Immunofluorescence of SOX4 in rat testis tissue with SOX4 antibody at 20 μg/mL.

Specification

Quantity

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