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KIRREL3 Antibody

Catalog # Availability Size / Price Inquiry
AMM06207G 0.1 mg / $695

KIRREL3 Antibody

Brand

Leading Biology

Catalog Number

AMM06207G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KIRREL3 antibody.

Molecular Weight

Predicted: 64, 84 kDa Observed: 60 kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

KIRREL3; KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.

Isotype

IgG

Symbol

KIAA1867, NEPH2

GeneID

UniProt ID

Function

Could be involved in the hematopoietic supportive capacity of stroma cells.

Summary

KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of KIRREL3 in mouse kidney tissue lysate with KIRREL3 antibody at (A) 1 and (B) 2 μg/ml.

Immunohistochemistry of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 5 μg/ml.

Immunofluorescence of KIRREL3 in mouse kidney tissue with KIRREL3 antibody at 20 μg/ml.

Specification

Quantity

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