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Polyclonal Antibodies >
CRH AntibodyBrand |
Leading Biology | Catalog Number |
APR11666G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CRH antibody.
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Molecular Weight |
Predicted: 22 kDa Observed: 29 kDa
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
CRH; CRH antibody is human specific.
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Function |
This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
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Summary |
Corticotropin-releasing hormone (CRH) is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress (1). In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta where it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturitio (2). Marked reduction in this protein has been observed in association with Alzheimer disease (3).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Images |
Western blot analysis of CRH in human placenta tissue lysate with CRH antibody at (A) 1 and (B) 2 μg/ml. Immunohistochemistry of CRH in human brain tissue with CRH antibody at 5 μg/mL. Immunofluorescence of CRH in human brain tissue with CRH antibody at 20 μg/mL. |
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Specification |
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Quantity |
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Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask | ||
3 | Leading Biology | APR13816G | TRPM5 Antibody | 50 μl | Polyclonal Antibodies |
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$695.00 | Add Ask | ||
4 | Leading Biology | APR04506G | PCOLCE2 Antibody (Center) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
5 | Leading Biology | APR26894N | ASPH Polyclonal Antibody | 100ul | Polyclonal Antibodies | Neuroscience>Calcium Signaling |
|
$495.00 | Add Ask | |
6 | Leading Biology | APR05221G | Phospho-SMAD2(S118) Antibody | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask |
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