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CCR7 Antibody

Catalog # Availability Size / Price Inquiry
APR15285G 0.1 mg / $695

CCR7 Antibody

Brand

Leading Biology

Catalog Number

APR15285G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CCR7 antibody.

Molecular Weight

Predicted: 42 kDa Observed: 42 kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Target

CCR7; CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.

Isotype

IgG

Symbol

CMKBR7, EBI1, EVI1

GeneID

UniProt ID

Function

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Summary

The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1,2). The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor (3).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 μg/ml.

Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 μg/mL.

Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 μg/mL.

Specification

Quantity

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