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RTN4RL2 Antibody

Catalog # Availability Size / Price Inquiry
APR13167G 0.1 mg / $695

RTN4RL2 Antibody

Brand

Leading Biology

Catalog Number

APR13167G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RTN4RL2 antibody.

Molecular Weight

Predicted: 46 kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor Note=Localized to the surface of neurons, including axons

Host

Rabbit

Species Reactivity

Human

Target

RTN4RL2; Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.

Isotype

IgG

GeneID

UniProt ID

Function

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Summary

RTN4RL2 Antibody: Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Images

Western blot analysis of RTN4RL2 in rat brain tissue lysate with RTN4RL2 antibody at 1 μg/mL.

Specification

Quantity

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